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Monoclonal antibodies against the 70-kilodalton iron-regulated protein of Neisseria meningitidis are bactericidal and strain specific.

When grown under iron limitation, Neisseria meningitidis expresses a number of outer membrane proteins (OMPs), one of which is a 70-kilodalton (kDa) major OMP. After immunization of mice with outer membrane preparations of iron-depleted cells of strain H44/76 (B:15:P1.7,16), hybridoma cell lines pro...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Pettersson, A, Kuipers, B, Pelzer, M, Verhagen, E, Tiesjema, R H, Tommassen, J, Poolman, J T
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1696939/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.9.3036-3041.1990
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