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Mutants of staphylococcal toxic shock syndrome toxin 1: mitogenicity and recognition by a neutralizing monoclonal antibody.

Toxic shock syndrome toxin 1 (TSST-1), a 22-kilodalton protein made by strains of Staphylococcus aureus harboring the chromosomal toxin gene, may elicit toxic shock syndrome in humans. In vitro, TSST-1 induces T cells to proliferate and macrophages to secrete interleukin-1. To conduct a structure-fu...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Blanco, L, Choi, E M, Connolly, K, Thompson, M R, Bonventre, P F
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313605/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1696937/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.9.3020-3028.1990
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