Discovery of Rare Mutations in Populations: TILLING by Sequencing(1)([C])([W])([OA])

Discovery of rare mutations in populations requires methods, such as TILLING (for Targeting Induced Local Lesions in Genomes), for processing and analyzing many individuals in parallel. Previous TILLING protocols employed enzymatic or physical discrimination of heteroduplexed from homoduplexed targe...

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Autori principali: Tsai, Helen, Howell, Tyson, Nitcher, Rebecca, Missirian, Victor, Watson, Brian, Ngo, Kathie J., Lieberman, Meric, Fass, Joseph, Uauy, Cristobal, Tran, Robert K., Khan, Asif Ali, Filkov, Vladimir, Tai, Thomas H., Dubcovsky, Jorge, Comai, Luca
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Plant Biologists 2011
Soggetti:
Breakthrough Technologies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135940/
https://ncbi.nlm.nih.gov/pubmed/21531898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.110.169748
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