Boronated Unnatural Cyclic Amino Acids as Potential Delivery Agents for Neutron Capture Therapy

Boron delivery characteristics of cis and trans isomers of a boronated unnatural amino acid, 1-amino-3-boronocyclopentanecarboxylic acid (ABCPC) were tested in B16 mouse model for human melanoma. Both ABCPC isomers delivered comparable boron to B16 melanoma tumor cells as L-p-boronophenylalanine (BP...

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Hauptverfasser: Kabalka, George W., Shaikh, Aarif L., Barth, Rolf F., Huo, Tianyao, Yang, Weilian, Gordnier, Pamela M., Chandra, Subhash
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135783/
https://ncbi.nlm.nih.gov/pubmed/21481596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2011.03.035
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