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(13)C–Metabolic enrichment of glutamate in glutamate dehydrogenase mutants of Saccharomyces cerevisiae

Glutamate dehydrogenases (GDH) interconvert α-ketoglutarate and glutamate. In yeast, NADP-dependent enzymes, encoded by GDH1 and GDH3, are reported to synthesize glutamate from α-ketoglutarate, while an NAD-dependent enzyme, encoded by GDH2, catalyzes the reverse. Cells were grown in acetate/raffino...

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Autori principali: Tang, Yijin, Sieg, Alex, Trotter, Pamela J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135716/
https://ncbi.nlm.nih.gov/pubmed/21242068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micres.2010.10.004
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