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NAD+ Depletion or PAR Polymer Formation: Which Plays the Role of Executioner in Ischemic Cell Death?

Multiple cell death pathways are activated in cerebral ischemia. Much of the initial injury, especially in the core of the infarct where cerebral blood flow is severely reduced, is necrotic and secondary to severe energy failure. However there is considerable evidence that delayed cell death continu...

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Hlavní autoři: Siegel, Chad, McCullough, Louise D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135708/
https://ncbi.nlm.nih.gov/pubmed/21091637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1748-1716.2010.02229.x
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