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NAD+ Depletion or PAR Polymer Formation: Which Plays the Role of Executioner in Ischemic Cell Death?

Multiple cell death pathways are activated in cerebral ischemia. Much of the initial injury, especially in the core of the infarct where cerebral blood flow is severely reduced, is necrotic and secondary to severe energy failure. However there is considerable evidence that delayed cell death continu...

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Autors principals: Siegel, Chad, McCullough, Louise D.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135708/
https://ncbi.nlm.nih.gov/pubmed/21091637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1748-1716.2010.02229.x
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