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Up-regulation of the mitochondrial malate dehydrogenase by oxidative stress is mediated by miR-743a
These experiments reveal for the first time that microRNAs mediate oxidant regulated expression of a mitochondrial tricarboxylic acid cycle gene (mdh2). mdh2 encoded malate dehydrogenase (MDH) is elevated by an unknown mechanism in brains of patients that died with Alzheimer’s disease (AD). Oxidativ...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135703/ https://ncbi.nlm.nih.gov/pubmed/21623795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07333.x |
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