Simulated Microgravity Compromises Mouse Oocyte Maturation by Disrupting Meiotic Spindle Organization and Inducing Cytoplasmic Blebbing

In the present study, we discovered that mouse oocyte maturation was inhibited by simulated microgravity via disturbing spindle organization. We cultured mouse oocytes under microgravity condition simulated by NASA's rotary cell culture system, examined the maturation rate and observed the spin...

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Bibliografiske detaljer
Main Authors: Wu, Changli, Guo, Xinzheng, Wang, Fang, Li, Xiaoshuang, Tian, X. Cindy, Li, Li, Wu, Zhenfang, Zhang, Shouquan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135614/
https://ncbi.nlm.nih.gov/pubmed/21765954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022214
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