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Simulated Microgravity Compromises Mouse Oocyte Maturation by Disrupting Meiotic Spindle Organization and Inducing Cytoplasmic Blebbing

In the present study, we discovered that mouse oocyte maturation was inhibited by simulated microgravity via disturbing spindle organization. We cultured mouse oocytes under microgravity condition simulated by NASA's rotary cell culture system, examined the maturation rate and observed the spin...

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Detalhes bibliográficos
Main Authors: Wu, Changli, Guo, Xinzheng, Wang, Fang, Li, Xiaoshuang, Tian, X. Cindy, Li, Li, Wu, Zhenfang, Zhang, Shouquan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135614/
https://ncbi.nlm.nih.gov/pubmed/21765954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022214
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