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A Novel Role of Protein Tyrosine Kinase2 in Mediating Chloride Secretion in Human Airway Epithelial Cells

Ca(2+) activated Cl(−) channels (CaCC) are up-regulated in cystic fibrosis (CF) airway surface epithelia. The presence and functional properties of CaCC make it a possible therapeutic target to compensate for the deficiency of Cl(−) secretion in CF epithelia. CaCC is activated by an increase in cyto...

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Autors principals: Liang, Lihua, Woodward, Owen M., Chen, Zhaohui, Cotter, Robert, Guggino, William B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135607/
https://ncbi.nlm.nih.gov/pubmed/21765932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021991
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