Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei

BACKGROUND: The ventral midbrain contains a diverse array of neurons, including dopaminergic neurons of the ventral tegmental area (VTA) and substantia nigra (SN) and neurons of the red nucleus (RN). Dopaminergic and RN neurons have been shown to arise from ventral mesencephalic precursors that expr...

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Bibliographic Details
Main Authors: Blaess, Sandra, Bodea, Gabriela O, Kabanova, Anna, Chanet, Soline, Mugniery, Emilie, Derouiche, Amin, Stephen, Daniel, Joyner, Alexandra L
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135491/
https://ncbi.nlm.nih.gov/pubmed/21689430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-6-29
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