Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer

Reduced epithelial cadherin (E-cad) is a hallmark of invasive carcinomas that have acquired epithelial-mesenchymal transition (EMT) phenotypes. Here we show that down-regulated E-cad expression induced by transforming growth factor-β (TGF-β) and EMT preceded breast cancer outgrowth in three-dimensio...

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Detaylı Bibliyografya
Asıl Yazarlar: Wendt, Michael K., Taylor, Molly A., Schiemann, Barbara J., Schiemann, William P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2011
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135469/
https://ncbi.nlm.nih.gov/pubmed/21613543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0306
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