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Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6

Natural killer (NK) cells are lymphocytes of the innate immune system that participate in the elimination of tumor cells. In humans, the activating natural cytotoxicity receptors (NCRs) NKp30, NKp44, and NKp46 play a major role in NK cell–mediated tumor cell lysis. NKp30 recognizes B7-H6, a member o...

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Autors principals: Li, Yili, Wang, Qian, Mariuzza, Roy A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135353/
https://ncbi.nlm.nih.gov/pubmed/21422170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102548
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