Dynamics of dibutyryl cyclic AMP- and prostaglandin E2-mediated suppression of lipopolysaccharide-induced tumor necrosis factor alpha gene expression.

The regulation of lipopolysaccharide (LPS)-induced tumor necrosis factor alpha (TNF) production by prostaglandin E2 (PGE2), forskolin, and dibutyryl cyclic AMP (cAMP) was examined at the cellular and molecular levels. The above three agents could suppress LPS (100 ng/ml)-stimulated TNF production by...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Spengler, R N, Spengler, M L, Lincoln, P, Remick, D G, Strieter, R M, Kunkel, S L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313535/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2547721/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.9.2837-2841.1989
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