Mutations in Bone Marrow-Derived Stromal Stem Cells Unmask Latent Malignancy

Neoplastic epithelia may remain dormant and clinically unapparent in human patients for decades. Multiple risk factors including mutations in tumor cells or the stromal cells may affect the switch from dormancy to malignancy. Gene mutations, including p53 mutations, within the stroma of tumors are a...

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Detalhes bibliográficos
Main Authors: Houghton, JeanMarie, Li, Hanchen, Fan, Xueli, Liu, Yingwang, Liu, Jian Hua, Rao, Varada P., Poutahidis, Theofilos, Taylor, Christie L., Jackson, Erin A., Hewes, Christine, Lyle, Stephen, Cerny, Anna, Bowen, Glennice, Cerny, Jan, Moore, Nathan, Kurt-Jones, Evelyn A., Erdman, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135253/
https://ncbi.nlm.nih.gov/pubmed/20199238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2009.0439
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