Individual Rac GTPases Mediate Aspects of Prostate Cancer Cell and Bone Marrow Endothelial Cell Interactions

The Rho GTPases organize the actin cytoskeleton and are involved in cancer metastasis. Previously, we demonstrated that RhoC GTPase was required for PC-3 prostate cancer cell invasion. Targeted down-regulation of RhoC led to sustained activation of Rac1 GTPase and morphological, molecular and phenot...

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Hlavní autoři: Chatterjee, Moumita, Sequeira, Linda, Jenkins-Kabaila, Mashariki, Dubyk, Cara W., Pathak, Surabhi, van Golen, Kenneth L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135208/
https://ncbi.nlm.nih.gov/pubmed/21776386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/541851
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