Individual Rac GTPases Mediate Aspects of Prostate Cancer Cell and Bone Marrow Endothelial Cell Interactions

The Rho GTPases organize the actin cytoskeleton and are involved in cancer metastasis. Previously, we demonstrated that RhoC GTPase was required for PC-3 prostate cancer cell invasion. Targeted down-regulation of RhoC led to sustained activation of Rac1 GTPase and morphological, molecular and phenot...

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Main Authors: Chatterjee, Moumita, Sequeira, Linda, Jenkins-Kabaila, Mashariki, Dubyk, Cara W., Pathak, Surabhi, van Golen, Kenneth L.
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2011
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135208/
https://ncbi.nlm.nih.gov/pubmed/21776386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/541851
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