Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

Coordinated transcription factor networks have emerged as the master regulatory mechanisms of stem cell pluripotency and differentiation. Many stem cell-specific transcription factors, including the pluripotency transcription factors, OCT4, NANOG, and SOX2 function in combinatorial complexes to regu...

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Detalhes bibliográficos
Main Authors: Kashyap, Vasundhra, Rezende, Naira C., Scotland, Kymora B., Shaffer, Sebastian M., Persson, Jenny Liao, Gudas, Lorraine J., Mongan, Nigel P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Comprehensive Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135180/
https://ncbi.nlm.nih.gov/pubmed/19480567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2009.0113
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