Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

Coordinated transcription factor networks have emerged as the master regulatory mechanisms of stem cell pluripotency and differentiation. Many stem cell-specific transcription factors, including the pluripotency transcription factors, OCT4, NANOG, and SOX2 function in combinatorial complexes to regu...

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Autors principals: Kashyap, Vasundhra, Rezende, Naira C., Scotland, Kymora B., Shaffer, Sebastian M., Persson, Jenny Liao, Gudas, Lorraine J., Mongan, Nigel P.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2009
Matèries:
Comprehensive Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135180/
https://ncbi.nlm.nih.gov/pubmed/19480567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2009.0113
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