Monoclonal antibodies that define neutralizing epitopes of pertussis toxin: conformational dependence and epitope mapping.

The epitope specificities of 13 hybridomas secreting monoclonal antibodies (MAbs) specific for pertussis toxin (PT) is described. Hybridoma lines were derived by the fusion of spleen cells from mice immunized with native PT, Formalin-detoxified PT, or isolated PT subunits (S1 to S5) with the myeloma...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Lang, A B, Ganss, M T, Cryz, S J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2474500/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.9.2660-2665.1989
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