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Traceless and Site-Specific Ubiquitination of Recombinant Proteins

[Image: see text] Protein ubiquitination is a post-translational modification that regulates almost all aspects of eukaryotic biology. Here we discover the first routes for the efficient site-specific incorporation of δ-thiol-l-lysine (7) and δ-hydroxy-l-lysine (8) into recombinant proteins, via evo...

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Bibliografiske detaljer
Main Authors: Virdee, Satpal, Kapadnis, Prashant B., Elliott, Thomas, Lang, Kathrin, Madrzak, Julia, Nguyen, Duy P., Riechmann, Lutz, Chin, Jason W.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2011
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135006/
https://ncbi.nlm.nih.gov/pubmed/21710965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja202799r
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