The Immunoglobulin super family protein RIG-3 prevents synaptic potentiation and regulates Wnt signaling

Cell surface Ig superfamily proteins (IgSF) have been implicated in several aspects of neuron development and function. Here, we describe a novel function for a C. elegans IgSF protein, RIG-3. Mutants lacking RIG-3 have an exaggerated paralytic response to a cholinesterase inhibitor, aldicarb. Altho...

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Hlavní autoři: Babu, Kavita, Hu, Zhitao, Chien, Shih-Chieh, Garriga, Gian, Kaplan, Joshua M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134796/
https://ncbi.nlm.nih.gov/pubmed/21745641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.05.034
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