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Enhanced Solubility, Stability, and Transcorneal Permeability of Delta-8-Tetrahydrocannabinol in the Presence of Cyclodextrins

The purpose of this study was to investigate the effect of cyclodextrins (CDs) on aqueous solubility, stability, and in vitro corneal permeability of delta-8-tetrahydrocannabinol (Δ(8)-THC). Phase solubility of Δ(8)-THC was studied in the presence of 2-hydroxypropyl-β-cyclodextrin (HPβCD), randomly...

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Detalhes bibliográficos
Main Authors: Hippalgaonkar, Ketan, Gul, Waseem, ElSohly, Mahmoud A., Repka, Michael A., Majumdar, Soumyajit
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134676/
https://ncbi.nlm.nih.gov/pubmed/21637944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9639-5
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