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Design and In Vitro Performance Evaluation of Purified Microparticles of Pravastatin Sodium for Intestinal Delivery

The purpose of research was to develop a mucoadhesive multiparticulate sustained drug delivery system of pravastatin sodium, a highly water-soluble and poorly bioavailable drug, unstable at gastric pH. Mucoadhesive microparticles were formulated using eudragit S100 and ethyl cellulose as mucoadhesiv...

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Detalhes bibliográficos
Main Authors: Garg, Yogesh, Pathak, Kamla
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134671/
https://ncbi.nlm.nih.gov/pubmed/21594729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9626-x
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