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Multivariate Analysis of Phenol in Freeze-Dried and Spray-Dried Insulin Formulations by NIR and FTIR

Dehydration is a commonly used method to stabilise protein formulations. Upon dehydration, there is a significant risk the composition of the formulation will change especially if the protein formulation contains volatile compounds. Phenol is often used as excipient in insulin formulations, stabilis...

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Detalhes bibliográficos
Main Authors: Maltesen, Morten Jonas, Bjerregaard, Simon, Hovgaard, Lars, Havelund, Svend, van de Weert, Marco, Grohganz, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134666/
https://ncbi.nlm.nih.gov/pubmed/21560023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9618-x
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