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Amphiphilic Erythromycin-Lipoamino Acid Ion Pairs: Characterization and In Vitro Microbiological Evaluation

A series of amphiphilic ion pairs of erythromycin (ERY) with lipoamino acids (LAAs) were produced. The ion pairs were prepared by evaporation of a water/ethanol co-solution of the drug and LAA bearing an alkyl side chain of 10–16 carbon atoms. For the sake of comparison, equimolar physical mixtures...

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Bibliografiset tiedot
Päätekijät: Pignatello, Rosario, Mangiafico, Annalisa, Ruozi, Barbara, Puglisi, Giovanni, Furneri, Pio Maria
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134655/
https://ncbi.nlm.nih.gov/pubmed/21479751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9605-2
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