Polyethyleneimine (PEI) Mediated siRNA Gene Silencing in the Schistosoma mansoni Snail Host, Biomphalaria glabrata

An in vivo, non-invasive technique for gene silencing by RNA interference (RNAi) in the snail, Biomphalaria glabrata, has been developed using cationic polymer polyethyleneimine (PEI) mediated delivery of long double-stranded (ds) and small interfering (si) RNA. Cellular delivery was evaluated and o...

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Hlavní autoři: Knight, Matty, Miller, Andre, Liu, Yijia, Scaria, Puthupparampil, Woodle, Martin, Ittiprasert, Wannaporn
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134429/
https://ncbi.nlm.nih.gov/pubmed/21765961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001212
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