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BK channels and a new form of hypertension

Large, Ca-activated K channels (BK) are comprised of an alpha pore (BKα) and one of four beta subunits (BKβ1-4). When the gene for BKβ1 is knocked out (BKβ1-KO) the result is increased myogenic tone of vascular smooth muscle and hypertension. We re-examined whether the hypertension is entirely due t...

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Bibliografiske detaljer
Main Authors: Grimm, P. Richard, Sansom, Steven C.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134256/
https://ncbi.nlm.nih.gov/pubmed/20720523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.272
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