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Activation of EGFR by proteasome inhibition requires HB-EGF in pancreatic cancer cells

Resistance to drug treatments underlies the high lethality of pancreatic ductal adenocarcinoma (PDA). We and others have recently identified that proteasome inhibition is a promising therapeutic option in this highly refractory disease. The pleiotropic effects of proteasome inhibition include the ac...

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Detalhes bibliográficos
Main Authors: Sloss, Callum M., Wang, Fang, Palladino, Michael A., Cusack, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134242/
https://ncbi.nlm.nih.gov/pubmed/20208558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.52
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