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Using Triplex-Forming Oligonucleotide Probes for the Reagentless, Electrochemical Detection of Double-Stranded DNA

We report a reagentless, electrochemical sensor for the detection of double-stranded DNA targets that employs triplex-forming oligonucleotides (TFOs) as its recognition element. These sensors are based on redox-tagged TFO probes strongly chemisorbed onto an interrogating gold electrode. Upon the add...

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Main Authors: Patterson, Adriana, Caprio, Felice, Vallée-Bélisle, Alexis, Moscone, Danila, Plaxco, Kevin W., Palleschi, Giuseppe, Ricci, Francesco
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134121/
https://ncbi.nlm.nih.gov/pubmed/20936782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1024528
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