Physiological Adaptation of the Bacterium Lactococcus lactis in Response to the Production of Human CFTR

Biochemical and biophysical characterization of CFTR (the cystic fibrosis transmembrane conductance regulator) is thwarted by difficulties to obtain sufficient quantities of correctly folded and functional protein. Here we have produced human CFTR in the prokaryotic expression host Lactococcus lacti...

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Bibliografiske detaljer
Main Authors: Steen, Anton, Wiederhold, Elena, Gandhi, Tejas, Breitling, Rainer, Slotboom, Dirk Jan
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134065/
https://ncbi.nlm.nih.gov/pubmed/21742800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M000052-MCP200
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