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Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment

Wnt signalling pathways have been shown to play key roles in both normal development and tumorigenesis. Progression of many human cancers is associated with defined mutations in Wnt pathway components that result in dysregulated β-catenin-mediated gene transcription. Although Wnt pathway mutations a...

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Detalhes bibliográficos
Main Authors: Barbolina, Maria V., Burkhalter, Rebecca J., Stack, M. Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133882/
https://ncbi.nlm.nih.gov/pubmed/21668411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110112
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