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Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment

Wnt signalling pathways have been shown to play key roles in both normal development and tumorigenesis. Progression of many human cancers is associated with defined mutations in Wnt pathway components that result in dysregulated β-catenin-mediated gene transcription. Although Wnt pathway mutations a...

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Bibliografische gegevens
Hoofdauteurs: Barbolina, Maria V., Burkhalter, Rebecca J., Stack, M. Sharon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133882/
https://ncbi.nlm.nih.gov/pubmed/21668411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110112
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