Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing

sFlt-1 (soluble Flt-1) potently inhibits angiogenesis by binding extracellularly to VEGF (vascular endothelial growth factor). In the present paper, we report that hypoxia down-regulates sFlt-1 expression in HMVECs (human microvascular endothelial cells), a constituent of microvessels where angiogen...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ikeda, Takayuki, Sun, Li, Tsuruoka, Naoki, Ishigaki, Yasuhito, Yoshitomi, Yasuo, Yoshitake, Yoshino, Yonekura, Hideto
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133880/
https://ncbi.nlm.nih.gov/pubmed/21382012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101490
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky