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Quantification of complex precore mutations of hepatitis B virus by SimpleProbe real time PCR and dual melting analysis

BACKGROUND: Hepatitis B virus (HBV) precore G1896A mutation is associated with Hepatitis B e antigen (HBeAg) seroconversion. This mutation and the adjacent G1899A mutation also appear to associate with increased risk of hepatocellular carcinoma. Quantitative mutant dynamics may help determine the po...

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Autors principals: Nie, Hui, Evans, Alison A., London, W. Thomas, Block, Timothy M., Ren, Xiangdong David
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133867/
https://ncbi.nlm.nih.gov/pubmed/21665530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcv.2011.05.020
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