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Imaging tumor hypoxia by near-infrared fluorescence tomography

We have developed a novel nitroimidazole indocyanine dye conjugate for tumor-targeted hypoxia fluorescence tomography. The hypoxia probe has been evaluated in vitro using tumor cell lines and in vivo with tumor targeting in mice. The in vitro cell studies were performed to assess fluorescence labeli...

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Detalhes bibliográficos
Main Authors: Biswal, Nrusingh C., Pavlik, Christopher, Smith, Michael B., Aguirre, Andres, Xu, Yan, Zanganeh, Saeid, Kuhn, Liisa T., Claffey, Kevin P., Zhu, Quing
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers (SPIE) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133800/
https://ncbi.nlm.nih.gov/pubmed/21721810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3589348
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