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Human DAZL, DAZ and BOULE genes modulate primordial germ cell and haploid gamete formation

The leading cause of infertility in men and women is quantitative and qualitative defects in human germ cell (oocyte and sperm) development. Yet, it has not been possible to examine the unique developmental genetics of human germ cell formation and differentiation due to inaccessibility of germ cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kee, Kehkooi, Angeles, Vanessa T, Flores, Martha, Nguyen, Ha Nam, Pera, Renee A Reijo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133736/
https://ncbi.nlm.nih.gov/pubmed/19865085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08562
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