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Human DAZL, DAZ and BOULE genes modulate primordial germ cell and haploid gamete formation

The leading cause of infertility in men and women is quantitative and qualitative defects in human germ cell (oocyte and sperm) development. Yet, it has not been possible to examine the unique developmental genetics of human germ cell formation and differentiation due to inaccessibility of germ cell...

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Autores principales: Kee, Kehkooi, Angeles, Vanessa T, Flores, Martha, Nguyen, Ha Nam, Pera, Renee A Reijo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133736/
https://ncbi.nlm.nih.gov/pubmed/19865085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08562
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