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Effect of a purA mutation on efficacy of Salmonella live-vaccine vectors.

We made delta aroA, delta purA, and delta aroA delta purA derivatives of a strain of Salmonella dublin and isolated a nalidixate-resistant mutant of each construct. An inoculum of each of the nearly isogenic nalidixate-resistant auxotrophs was administered to BALB/c mice by gavage. The ability of ea...

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Hlavní autoři: Sigwart, D. F., Stocker, B. A., Clements, J. D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC313368/
https://ncbi.nlm.nih.gov/pubmed/2722244
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