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Effect of a purA mutation on efficacy of Salmonella live-vaccine vectors.

We made delta aroA, delta purA, and delta aroA delta purA derivatives of a strain of Salmonella dublin and isolated a nalidixate-resistant mutant of each construct. An inoculum of each of the nearly isogenic nalidixate-resistant auxotrophs was administered to BALB/c mice by gavage. The ability of ea...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Sigwart, D. F., Stocker, B. A., Clements, J. D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313368/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2722244/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.6.1858-1861.1989
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