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Genetic analysis of new 16S rRNA mutations conferring aminoglycoside resistance in Mycobacterium abscessus

OBJECTIVES: We studied the development and fitness cost of 2-deoxystreptamine aminoglycoside resistance of Mycobacterium abscessus. METHODS: Spontaneous 2-deoxystreptamine aminoglycoside-resistant mutants were selected and the frequency of their appearance was determined. The 3′ part of the rrs gene...

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Bibliographic Details
Main Authors: Nessar, Rachid, Reyrat, Jean Marc, Murray, Alan, Gicquel, Brigitte
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133489/
https://ncbi.nlm.nih.gov/pubmed/21652621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkr209
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