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Cross-Reactive Human IgM-Derived Monoclonal Antibodies that Bind to HIV-1 Envelope Glycoproteins

Elicitation of antibodies with potent and broad neutralizing activity against HIV by immunization remains a challenge. Several monoclonal antibodies (mAbs) isolated from humans with HIV-1 infection exhibit such activity but vaccine immunogens based on structures containing their epitopes have not be...

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Библиографические подробности
Главные авторы: Chen, Weizao, Zhu, Zhongyu, Liao, Huaxin, Quinnan, Gerald V., Broder, Christopher C., Haynes, Barton F., Dimitrov, Dimiter S.
Формат: Artigo
Язык:Inglês
Опубликовано: Molecular Diversity Preservation International (MDPI) 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133461/
https://ncbi.nlm.nih.gov/pubmed/21755021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2020547
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