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Kinase Suppressor of Ras 1 (KSR1) Regulates PGC1α and Estrogen-Related Receptor α To Promote Oncogenic Ras-Dependent Anchorage-Independent Growth

Kinase suppressor of ras 1 (KSR1) is a molecular scaffold of the Raf/MEK/extracellular signal-regulated kinase (ERK) cascade that enhances oncogenic Ras signaling. Here we show KSR1-dependent, but ERK-independent, regulation of metabolic capacity is mediated through the expression of peroxisome prol...

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Bibliografische gegevens
Hoofdauteurs: Fisher, Kurt W., Das, Binita, Kortum, Robert L., Chaika, Oleg V., Lewis, Robert E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133429/
https://ncbi.nlm.nih.gov/pubmed/21518958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05255-11
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