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ck2-Dependent Phosphorylation of Progesterone Receptors (PR) on Ser81 Regulates PR-B Isoform-Specific Target Gene Expression in Breast Cancer Cells

Progesterone receptors (PR) are critical mediators of mammary gland development and contribute to breast cancer progression. Progestin-induced rapid activation of cytoplasmic protein kinases leads to selective regulation of growth-promoting genes by phospho-PR species. Herein, we show that phosphory...

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Bibliografske podrobnosti
Main Authors: Hagan, Christy R., Regan, Tarah M., Dressing, Gwen E., Lange, Carol A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133426/
https://ncbi.nlm.nih.gov/pubmed/21518957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01246-10
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