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Gamma Interferon Modulates Myogenesis through the Major Histocompatibility Complex Class II Transactivator, CIITA

Gamma interferon (IFN-γ) is an inflammatory cytokine that has complex effects on myogenesis. Here, we show that the IFN-γ-induced inhibition of myogenesis is mediated by the major histocompatibility complex (MHC) class II transactivator, CIITA, which binds to myogenin and inhibits its activity. In I...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Londhe, Priya, Davie, Judith K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133399/
https://ncbi.nlm.nih.gov/pubmed/21576360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05397-11
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