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Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells

Ferritin is a cytosolic protein that stores excess iron, thereby protecting cells from iron toxicity. Ferritin-stored iron is believed to be utilized when cells become iron deficient; however, the mechanisms underlying the extraction of iron from ferritin have yet to be fully elucidated. Here, we de...

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Detalhes bibliográficos
Main Authors: Asano, Takeshi, Komatsu, Masaaki, Yamaguchi-Iwai, Yuko, Ishikawa, Fuyuki, Mizushima, Noboru, Iwai, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133360/
https://ncbi.nlm.nih.gov/pubmed/21444722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01437-10
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