BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair

DNA damage activates signaling pathways that lead to modification of local chromatin and recruitment of DNA repair proteins. Multiple DNA repair proteins having ubiquitin ligase activity are recruited to sites of DNA damage, where they ubiquitinate histones and other substrates. This DNA damage-indu...

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Main Authors: Ginjala, Vasudeva, Nacerddine, Karim, Kulkarni, Atul, Oza, Jay, Hill, Sarah J., Yao, Ming, Citterio, Elisabetta, van Lohuizen, Maarten, Ganesan, Shridar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133356/
https://ncbi.nlm.nih.gov/pubmed/21383063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00981-10
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