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A Conserved Patch near the C Terminus of Histone H4 Is Required for Genome Stability in Budding Yeast
A screen of Saccharomyces cerevisiae histone alanine substitution mutants revealed that mutations in any of three adjacent residues, L97, Y98, or G99, near the C terminus of H4 led to a unique phenotype. The mutants grew slowly, became polyploid or aneuploid rapidly, and also lost chromosomes at a h...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133250/ https://ncbi.nlm.nih.gov/pubmed/21444721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01432-10 |
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