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Complex Transcriptional Control of the Antibiotic Regulator afsS in Streptomyces: PhoP and AfsR Are Overlapping, Competitive Activators

The afsS gene of several Streptomyces species encodes a small sigma factor-like protein that acts as an activator of several pathway-specific regulatory genes (e.g., actII-ORF4 and redD in Streptomyces coelicolor). The two pleiotropic regulators AfsR and PhoP bind to overlapping sequences in the −35...

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Detalhes bibliográficos
Main Authors: Santos-Beneit, Fernando, Rodríguez-García, Antonio, Martín, Juan F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133061/
https://ncbi.nlm.nih.gov/pubmed/21378195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01462-10
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