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Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity

Adipose tissue secretes proteins referred to as adipokines, many of which promote inflammation and disrupt glucose homeostasis. Here we show that secreted frizzled-related protein 5 (Sfrp5), a protein previously linked to the Wnt signaling pathway, is an anti-inflammatory adipokine whose expression...

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Detalhes bibliográficos
Main Authors: Ouchi, Noriyuki, Higuchi, Akiko, Ohashi, Koji, Oshima, Yuichi, Gokce, Noyan, Shibata, Rei, Akasaki, Yuichi, Shimono, Akihiko, Walsh, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132938/
https://ncbi.nlm.nih.gov/pubmed/20558665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188280
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