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Mutations in the hemolytic-phospholipase C operon result in decreased virulence of Pseudomonas aeruginosa PAO1 grown under phosphate-limiting conditions.

The phospholipase C (PLC) operon of Pseudomonas aeruginosa consists of plcS, which encodes a heat-labile secreted hemolysin, and two in-phase, overlapping genes, plcR1 and plcR2, which may encode Pi-regulatory genes. A 2.8-kilobase-pair deletion mutation in this operon was constructed, and a tetracy...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Ostroff, R M, Wretlind, B, Vasil, M L
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313284/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2496027/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.5.1369-1373.1989
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