تحميل...
Adoption of an “Open” Envelope Conformation Facilitating CD4 Binding and Structural Remodeling Precedes Coreceptor Switch in R5 SHIV-Infected Macaques
A change in coreceptor preference from CCR5 to CXCR4 towards the end stage disease in some HIV-1 infected individuals has been well documented, but the reasons and mechanisms for this tropism switch remain elusive. It has been suggested that envelope structural constraints in accommodating amino aci...
محفوظ في:
المؤلفون الرئيسيون: | , , , , , , , |
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التنسيق: | Artigo |
اللغة: | Inglês |
منشور في: |
Public Library of Science
2011
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الموضوعات: | |
الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132741/ https://ncbi.nlm.nih.gov/pubmed/21760891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021350 |
الوسوم: |
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