Remodeling Lipid Metabolism and Improving Insulin Responsiveness in Human Primary Myotubes

OBJECTIVE: Disturbances in lipid metabolism are strongly associated with insulin resistance and type 2 diabetes (T2D). We hypothesized that activation of cAMP/PKA and calcium signaling pathways in cultured human myotubes would provide further insight into regulation of lipid storage, lipolysis, lipi...

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Bibliografiske detaljer
Main Authors: Sparks, Lauren M., Moro, Cedric, Ukropcova, Barbara, Bajpeyi, Sudip, Civitarese, Anthony E., Hulver, Matthew W., Thoresen, G. Hege, Rustan, Arild C., Smith, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132732/
https://ncbi.nlm.nih.gov/pubmed/21760887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021068
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