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Diphosphoryl lipid A from Rhodopseudomonas sphaeroides ATCC 17023 blocks induction of cachectin in macrophages by lipopolysaccharide.

Purified diphosphoryl lipid A (DPLA) obtained from the nontoxic lipopolysaccharide of Rhodopseudomonas sphaeroides ATCC 17023 was shown to block the induction of cachectin (tumor necrosis factor) in the RAW 264.7 macrophage cell line by toxic deep-rough-chemotype lipopolysaccharide (ReLPS) of Escher...

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Main Authors: Takayama, K, Qureshi, N, Beutler, B, Kirkland, T N
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC313273/
https://ncbi.nlm.nih.gov/pubmed/2784418
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