Absence of Rac1 and Rac3 GTPases in the nervous system hinders thymic, splenic and immune-competence development

The nervous system influences organ development by direct innervation and the action of hormones. We recently showed that the specific absence of Rac1 in neurons (Rac1(N)) in a Rac3-deficient (Rac3(KO)) background causes motor behavioural defects, epilepsy, and premature mouse death around postnatal...

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Bibliografiska uppgifter
Huvudupphovsmän: Basso, Veronica, Corbetta, Sara, Gualdoni, Sara, Tonoli, Diletta, Poliani, Pietro Luigi, Sanvito, Francesca, Doglioni, Claudio, Mondino, Anna, de Curtis, Ivan
Materialtyp: Artigo
Språk:Inglês
Publicerad: WILEY-VCH Verlag 2011
Ämnen:
Immunomodulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132589/
https://ncbi.nlm.nih.gov/pubmed/21469092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040892
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